Cord Blood Banking

As expecting parents, you have a once-in-a-lifetime chance of capturing powerful stem cells at the time of birth.

Cord blood is the blood that is left in the umbilical cord once it is clamped and cut after birth. It is an abundant source of valuable stem cells that are currently being used to treat life-threatening conditions and are a subject of many on-going clinical trials.

Major Types of Stem Cells Within the Cord Blood

Hematopoietic Stem Cells (HSCs)
Mesenchymal Stem Cells (MSCs)
Very Small Embryonic-Like Stem Cells (VSELs)

Description
Description
Description

What Is It and What They Do

The blood-forming stem cells in cord blood. They create all types of blood and immune cells and are already used in transplants for conditions like leukemia, lymphoma, sickle cell disease, and immune deficiencies.
Special cells in cord blood that can grow into bone, cartilage, and fat cells. They also help reduce inflammation and support repair of damaged tissues.
Tiny, primitive cells found in cord blood that may act as a “reserve” of early stem cells. Scientists believe they may develop into many different tissue types.

Looking Ahead

Researchers are finding ways to expand HSCs in the lab so that one cord blood unit can treat more patients.[1]
Studies suggest MSCs may be used in regenerative therapies for arthritis, immune disorders, and tissue injuries.[2]
Still under study, VSELs could one day be used for organ repair and advanced regenerative medicine.[3]

What is Cord Blood Banking?

Cord blood banking involves collecting the blood that remains in your baby’s umbilical cord after birth — a simple procedure performed by your doctor or midwife. The cord blood is then delivered to our laboratory, where it is tested, processed, and securely preserved for long-term storage. This ensures your family has access to a valuable source of stem cells that may be used in approved medical treatments in the future.

1. Sign up to cord blood banking

2. Cord blood collection at birth

3. Sample processing & storage

Advanced Technology for Cord Blood Banking

CellAdvance™ is our premium cord blood banking service designed to maximize the recovery of viable stem cells and minimize contamination.

We use an FDA-approved processing technology that provides the highest stem cell yield and purity, supporting a wider range of potential future therapies.

  • Maximizes colony-forming stem cell (CFU) recovery.
  • Reduces red blood cell contamination by up to 99%.
  • Higher stem cell yield may support faster engraftment in clinical use.
  • Designed to preserve the largest possible number of viable stem cells for long-term storage.

Who Can Use Your Baby’s Cord Blood?

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Perfect Match for Your Baby

Cord blood is a perfect genetic match for your child, offering the highest compatibility for potential treatments.

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Potential Match for Siblings

There is 25% chance of a perfect match to siblings, making cord blood a valuable resource for your other kids as well.

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Partial Match for Parents

Parents are 50% partial match, which could provide certain therapeutic options in some medical situations.

FDA-Approved Cord Blood Treatments

Stem cells from cord blood can treat over 80 medical conditions.

Leukemia (Blood Cancers)

Cancers of the blood and bone marrow caused by uncontrolled growth of abnormal white blood cells.

  • Acute Lymphoblastic Leukemia (ALL)
  • Acute Myelogenous Leukemia (AML)
  • Acute Biphenotypic Leukemia
  • Acute Undifferentiated Leukemia
  • Chronic Lymphocytic Leukemia (CLL)
  • Chronic Myelogenous Leukemia (CML)
  • Juvenile Chronic Myelogenous Leukemia (JCML)
  • Juvenile Myelomonocytic Leukemia (JMML)
Pre-Leukemia & Bone Marrow Disorders

Disorders in which the bone marrow makes too few or defective blood cells, often preceding leukemia.

  • Myelodysplastic Syndrome (MDS)
  • Refractory Anemia
  • Refractory Anemia with Ringed Sideroblasts (RARS)
  • Refractory Anemia with Excess Blasts (RAEB)
  • Refractory Anemia with Excess Blasts in Transformation (RAEB-T)
  • Chronic Myelomonocytic Leukemia (CMML)
Lymphoma (Lymphatic System Cancers)

Cancers that start in the lymphatic system, affecting lymph nodes and immune cells.

  • Hodgkin’s Lymphoma
  • Non-Hodgkin’s Lymphoma (Burkitt’s Lymphoma)
Red Blood Cell Disorders

Conditions where red blood cells are reduced or dysfunctional, lowering oxygen delivery.

  • Aplastic Anemia
  • Fanconi Anemia
  • Congenital Dyserythropoietic Anemia
  • Paroxysmal Nocturnal Hemoglobinuria (PNH)
  • Sickle Cell Disease
  • Beta Thalassemia Major (Cooley’s Anemia)
  • Diamond-Blackfan Anemia
  • Pure Red Cell Aplasia
Platelet Disorders

Conditions affecting platelet production or function, causing abnormal clotting.

  • Amegakaryocytosis / Congenital Thrombocytopenia
  • Glanzmann Thrombasthenia
Immune System Disorders

Disorders where the immune system is absent, weak, or not functioning properly, leading to infections.

  • Severe Combined Immunodeficiency (SCID)
  • SCID with Adenosine Deaminase Deficiency (ADA-SCID)
  • X-linked SCID
  • SCID with absence of T & B cells
  • SCID with absence of T cells, normal B cells
  • Omenn Syndrome
Inherited Neutropenia Disorders

Disorders with abnormally low neutrophils, increasing infection risk.

  • Infantile Genetic Agranulocytosis (Kostmann Syndrome)
  • Myelokathexis
Other Inherited Immune Disorders

Miscellaneous inherited immune disorders not classified under immunodeficiency or neutropenia.

  • Ataxia-Telangiectasia
  • Bare Lymphocyte Syndrome
  • Common Variable Immunodeficiency
  • DiGeorge Syndrome
  • Hemophagocytic Lymphohistiocytosis (HLH)
  • Leukocyte Adhesion Deficiency
  • Lymphoproliferative Disorders
  • Lymphoproliferative Disorder, X-linked (EBV susceptibility)
  • Wiskott-Aldrich Syndrome
Myeloproliferative Disorders

Disorders causing excessive production of blood cells in the bone marrow.

  • Acute Myelofibrosis
  • Agnogenic Myeloid Metaplasia (Myelofibrosis)
  • Polycythemia Vera
  • Essential Thrombocythemia
Phagocyte Disorders

Disorders where phagocytes cannot effectively engulf and destroy pathogens.

  • Chediak-Higashi Syndrome
  • Chronic Granulomatous Disease
  • Neutrophil Actin Deficiency
  • Reticular Dysgenesis
Bone Marrow Cancers

Malignancies originating in bone marrow, often involving plasma cells or other marrow cells.

  • Multiple Myeloma
  • Plasma Cell Leukemia
  • Waldenström’s Macroglobulinemia
Inherited Disorders

Genetic conditions passed through families, affecting multiple organs or systems.

  • Cartilage-Hair Hypoplasia
  • Erythropoietic Porphyria
  • Hermansky-Pudlak Syndrome
  • Pearson’s Syndrome
  • Shwachman-Diamond Syndrome
  • Systemic Mastocytosis
Metabolic & Lysosomal Disorders

Disorders affecting metabolic pathways, causing accumulation of substances in lysosomes.

  • Amyloidosis
  • Hurler Syndrome (MPS-IH)
  • Scheie Syndrome (MPS-IS)
  • Hunter Syndrome (MPS-II)
  • Sanfilippo Syndrome (MPS-III)
  • Morquio Syndrome (MPS-IV)
  • Maroteaux-Lamy Syndrome (MPS-VI)
  • Sly Syndrome (MPS-VII)
  • Mucolipidosis II (I-cell disease)
  • Adrenoleukodystrophy (ALD)
  • Krabbe Disease (Globoid Cell Leukodystrophy)
  • Metachromatic Leukodystrophy
  • Pelizaeus-Merzbacher Disease
  • Niemann-Pick Disease
  • Sandhoff Disease
  • Wolman Disease
  • Lesch-Nyhan Syndrome
  • Osteopetrosis
  • Tay-Sachs Disease
  • Gaucher Disease
  • Mannosidosis
Solid Tumors

Malignant growths in tissues or organs outside of blood and bone marrow.

  • Neuroblastoma
  • Medulloblastoma
  • Retinoblastoma

Clinical Trials and Odds of Using Cord Blood Stem Cells

Cerebral Palsy

Cerebral Palsy (CP) results from brain injury or oxygen deprivation before or during birth, or in early childhood. It can hinder movement, learning, hearing, vision, and cognitive abilities. “Cerebral” relates to the brain, while “palsy” refers to muscle weakness or usage difficulties. CP stands as the most prevalent motor disability in childhood.

The potential of cord blood stem cells:
Anti-Inflammatory Properties
Preliminary studies indicate that cells in cord blood can regulate inflammation and move to areas of neurological injury.
Bystander Effect
Earlier pre-clinical studies revealed that cord blood stem cells are capable of reducing inflammation and modifying synaptic connections through paracrine signaling. Initial trials have indicated that infusing cord blood may enhance both gross and fine motor skills and boost overall brain connectivity.
Safe and Accessible
At birth, cord blood can be readily collected and preserved for potential future use by the newborn or a close family member.

Source: CBR

Autism

Autism, also known as Autism Spectrum Disorder (ASD), is a multifaceted condition characterized by diverse signs and symptoms. While no two individuals with autism are identical, they may share challenges in language and social interaction. Researchers aim to discover treatments that can soothe this hyperactive immune response, potentially safeguarding the developing brains of children with autism.

The potential of cord blood stem cells:
Anti-Inflammatory Properties
Preliminary studies indicate that cells in cord blood can regulate inflammation and move to areas of neurological injury.
Bystander Effect
Earlier pre-clinical studies revealed that umbilical cord blood (CB) contains cells capable of reducing inflammation and modifying synaptic connections through paracrine signaling.
Safe and Accessible
At birth, cord blood can be readily collected and preserved for potential future use by the newborn or a close family member.

Source: CBR

Hearing Loss

Sensorineural hearing loss (SNHL) is a distinct form of hearing impairment attributed to inner ear damage or dysfunction, as opposed to other ear structures. Acquired SNHL can arise from premature birth, infections, or exposure to loud noise or specific medications, leading to irreversible harm to the delicate hair cells (cilia) in the inner ear.

The potential of cord blood stem cells:
Targeted Therapy
Early laboratory research indicates that cord blood stem cells may uniquely target the root cause of hearing loss by assisting in the regeneration of delicate structures within the inner ear.
Self Repair
Laboratory studies have revealed that newborn stem cells possess the capacity to target damaged areas and potentially stimulate repair mechanisms at those sites.
Safe and Accessible
At birth, cord blood can be readily collected and preserved for potential future use by the newborn or a close family member.

Source: CBR

More Conditions Under Clinical Trial for Autologous Treatment

Autism
Cerebral Palsy
Hearing Loss (acquired sensorineural)
Hypoxic Ischemic Encephalopathy (HIE)
Amyotrophic Lateral Sclerosis (ALS)
Crohn’s Disease
Type 1 Diabetes
Lupus
Multiple Sclerosis
Scleroderma
Support for Misc. Open Cardiac Surgery
Hypoplastic Left Heart Syndrome (HLHS)
Grow Vascular Graft
Critical Limb Ischemia
Compartment Syndrome
Ischemic Stroke
Ischemic Heart Disease
Myocardial Infarction
Cardiomyopathy
Alveolar Cleft Palate Repair
Knee Cartilage Repair

Cord Blood Banking FAQs

What is the difference between public and private cord blood banking?

Public cord blood banks store donated cord blood for use by anyone who may need it for medical treatment, similar to a blood donation system. Private cord blood banks, on the other hand, store your baby’s cord blood exclusively for your family’s exclusive use. This ensures that the stem cells are readily available if your child or a family member requires them in the future.

Can I still collect cord blood if I have a cesarean section (C-section)?

Yes, cord blood can be collected during C-sections. The collection process is safe and does not interfere with the surgery or the care of you and your baby. Your healthcare team will coordinate with the cord blood bank to ensure proper collection.

How long can cord blood be stored?

Cord blood can be stored safely for decades when preserved under controlled cryogenic conditions. Research led by Dr. Hal Broxmeyer has demonstrated that cryopreserved cord blood remains viable after 27 years in frozen storage. In 2018, Australia’s BMDI public cord blood bank successfully transplanted a leukemia patient with a donor cord blood unit that had been in storage for 20 years.

Ready to Learn More? Start with our Free Info Pack

Our free info pack walks you through everything — what are newborn stem cells, how private stem cell banking works, why it matters, and which options are best for your family. It’s a helpful starting point for parents exploring cord blood banking.